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Laboratory Medicine

Test catalogue

Serotonin (5-Hydroxytryptamine)

Test Name

Serotonin (5-Hydroxytryptamine)

Gold Tube Specimen Type / Requirements

Container Type = 1 Gold Top Tube (SST)

Minimum Volume = 3 mL serum

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions: Ensure both sample and requisition are labelled properly. Serotonin may be increased by diet or released by medications. For 48 h prior to collection, patient must abstain from avocados, bananas, coffee, plums, pineapples, tomatoes, walnuts, hickory nut, mollusks, eggplant and medications such as aspirin, cortocotropins, MAO inhibitors, phenacetin, catecholamines, reserpine and nicotine. Write your initials, date and time of collection on the collection label.

Laboratory Staff Instructions Separate from cells as soon as possible. Store and send frozen. If the specimen thaws it is unsuitable for analysis

Rejection Criteria: Plasma, Unlabeled or Not Sufficient Quantity Samples will be rejected.

Stability: Stable at room temperature for 2 hours, refrigerated for 6 hours and frozen more than 6 hours.

Transportation: Send sample to core lab as soon as possible.

Required Documentation

Turnaround Time (TAT)

20 Days

Test Utilization

Reference Value

170 - 1134 nmol/L

Test Code




Testing Location

Referred Out – ON, Canada (ROICL02)

Other Information

Last Updated: June 06, 2019