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Laboratory Medicine

Test Catalogue

Beta-Crosslaps (CTx, Beta-CTx, C-Telopeptide, Carboxy terminal collagen crosslinks)

Test Name

Beta-Crosslaps (CTx, Beta-CTx, C-Telopeptide, Carboxy terminal collagen crosslinks)

Gold Tube Specimen Type / Requirements

Container Type = 1 Gold Top (SST)

Minimum Volume = 2 ml Blood

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions: It is recommended to draw blood as fasting or morning samples. Collect sample in vacutainer with or without gel separator. Plasma collected in EDTA or heparin containing vacutainer (lavender or green top) are acceptable too. Write your initials, date and time of collection on the collection label or requisition.

Special Instructions Serum free from hemolysis. Separate samples from cells as soon as possible. Repeated freezing and thawing of samples should be avoided

Rejection Criteria: Grossly Hemolyzed and icteric samples, Unlabeled or Not Sufficient Quantity Samples will be rejected. Hemolyzed sample (Hb > 5 g/L) will elicit a decrease in the β-CTx concentration

Stability: Stable for 8hrs at room temperature, refrigerated 1 week and 3 months stored at -20C or colder.

Transportation: Send sample to core lab as soon as possible.

Required Documentation

1 hour for Trauma/Stat - 2 hours for routine

2 hours for routine

Test Utilization


Reference Value

Males (30-70 years): 100 – 500 ng/L

Males (>70 years): 150 – 700 ng/L

Female (Pre-menopausal): 150 – 600 ng/L

Female (Post-menopausal): 200 – 900 ng/L

Test Code



Chemiluminescent Assay

Testing Location


Other Information

Last Updated: June 06, 2019