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Keenan Research Centre

Scientist Profiles

Minna Woo

MD, University of Toronto; FRCPC (General Internal Medicine and Endocrinology), University of Toronto; PhD (Immunology), University of Toronto

Affiliations

Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital

Staff Endocrinologist, Internal Medicine and Endocrinology, St. Michael's Hospital

Assistant Professor, Medicine, University of Toronto

Assistant Professor, Medical Biophysics, University of Toronto

Assistant Professor, Institute of Medical Science, University of Toronto

Clinical Specialty

Endocrinology

Research Interests

Type 1 and type 2 diabetes, pancreatic beta cell apoptosis, caspases, insulin signaling, gene targeting, knockout mice

Selected Publications

Link to Pub Med

Research Activities

The major research interest in my laboratory is to elucidate the mechanisms of islet apoptosis in vivo and ex vivo, using genetic approaches towards diabetes prevention and treatment, as well as successful islet transplantation. We use knockout mouse models of genes involved in the apoptotic pathway such as Caspases which serve as great tools to study the signaling events of islet apoptosis during 1) initiation of autoimmune diabetes, 2) the final destructive phase of the islets in both type 1 and 2 diabetes and 3) in islet transplantation.

Other Activities

1. Vice Chair, Personnel and Awards Peer Review Committee, Canadian Diabetes Association
2. Vice Chair Scientific elect, Clinical and Scientific Section of the Canadian Diabetes Association
3. National Research Council Member, Canadian Diabetes Association
4. Editorial Board Member, American Journal of Physiology Endocrinology and Metabolism
5. Panel Member for Canadian Institutes of Health Research, Diabetes, Obesity and Lipoprotein peer review committee
6. Ad hoc reviewer for the following journals PNAS, Diabetes, Endocrinology, Endocrine, International Immunology

Educational Activities

Graduate student supervision (2 PhD, 3 MSc candidates, 1 PDF)

International Graduate Student supervision

Undergraduate Student supervision for Human Biology Porject course HBL499

Contact

Phone: 416-867-7460 Ext. 8231
Fax: 416-867-3696
E-mail: WooM@smh.ca
Website: http://medbio.utoronto.ca/faculty/woo.html