Keenan Research Centre

Scientist Profiles

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Jeremy A. Scott

PhD (pharmacology and toxicology), University of Western Ontario; M.Sc. (pharmacology), University of Western Ontario; B.Sc.(pharmacology and toxicology), University of Western Ontario

Affiliations

Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital

Assistant Professor and Research Scientist, Department of Medicine, Divisions of Occupational and Respiratory Medicine, University of Toronto

Research Interests

Asthma, occupational and environmental exposures, murine model, airways responsiveness

Selected Publications

Link to Pub Med

Research Activities

My primary research interests are focused on the fundamental mechanisms of the development of airways hyperresponsiveness and remodeling in asthma, as well as the impact of occupational and environmental exposures on asthma exacerbations. Specifically, currently funded investigations are 1) examining the role of dysfunction of L-arginine metabolism in the development of airways hyperresponsiveness and remodeling in asthma; 2) examining the impact of exposure to particulate air pollutants on the exacerbation of airways symptoms in human asthmatics and mouse models of asthma; and 3) examining respiratory effects of exposure to occupational environmental contaminants. My laboratory primarily utilizes in vivo human exposures and animal models of airways disease, as well as in vitro studies of airway epithelial cells. Specific techniques used in these investigations include pulmonary function testing in mice, protein and RNA analyses, and gene expression microarrays.

Other Activities

  1. Steering Committee, Canadian Group for Food Allergy Research (CanGoFAR)
  2. Planning Committee, AllerGen NCE Scientific Meeting 2008: Environmental Exposure Workshop
  3. Steering Committee, AllerGen NCE Programme, A-Gene/Environment Interactions
  4. Steering Committee, Southern Ontario Centre for Atmospheric and Aerosol Research

Educational Activities

I have an appointment in the Department of Medicine (Divisions of Respiratory and Occupational Medicine) and an Associate Graduate Appointment with the Institutes of Medical Sciences. I currently supervise one PhD student and two postdoctoral fellows.

Contact

Phone: 416-946-0961
Fax: 416-978-8765
E-mail: jeremy.scott@utoronto.ca
Website: http://www.utoronto.ca/respirology/who/Jeremy_Scott.html
Website: http://www.socaar.utoronto.ca/personnel/Management.htm
Website: http://www.occupationalmedicine.utoronto.ca/people/faculty.htm

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