Keenan Research Centre

Scientist Profiles

Alexander D. Romaschin

PhD (chemistry), University of Windsor; DCC (clinical biochemistry), University of Toronto; FCACB (clinical biochemistry)

Affiliations

Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital

Head, Clinical Biochemistry, St. Michael's Hospital

Associate Professor, Lab Medicine and Surgery, University of Toronto

Clinical Specialty

Biochemistry

Research Interests

Endotoxemia, therapeutic aptamer development, mass spectrometry

Selected Publications

Link to Pub Med

Research Activities

Biomarkers of endometrial and ovarian cancer: discovery and validation using LC/MS/MS and molecular approaches. Our group has identified over 25 proteins which are over-expressed in Endometrial and Ovarian cancers. A number of these proteins are potential drug targets.

Therapeutic aptamer development: we are utilizing DNA based recognitive ligands to replace antibodies as potential diagnostic and therapeutic tools in cancer therapy and treatment of septic shock.

Educational Activities

Member of School of Graduate Studies, Dept. of Lab Medicine and Pathobiology and Dept. of Surgery. Interested predominantly in postdoctoral fellows.

Contact

Phone: 416-360-4000 Ext. 2226
Fax: 416-864-5194
E-mail: RomaschinA@smh.ca