Keenan Research Centre
Scientist Profiles
Gerald J. Prud'homme
MD, University of Ottawa; FRCPC (anatomical pathology), University of Toronto, University of Ottawa and McGill University
Affiliations
Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital
Professor, Laboratory Medicine and Pathobiology, University of Toronto
Clinician-Scientist, Laboratory Medicine, St. Michael's Hospital
Staff Pathologist and Director of the Autopsy Service, Division of Pathology, St. Michael's Hospital
Member, Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto
Research Interests
Autoimmune diseases, DNA vaccination, gene therapy, diabetes, tumour immunology
Selected Publications
Research Activities
My main research interests are in the areas of autoimmune diseases, tumour immunotherapy and gene therapy. My laboratory has developed a method of non-viral gene transfer that can be utilized for intra-muscular transfer of genes or DNA vaccination. We are currently studying the role of neuropilins in TGF-beta activation, immune regulation and cancer biology. In addition, we are investigating the aryl hydrocarbon receptor as a drug target for the therapy of breast cancer, the inhibition of cancer stem cells, and the prevention of metastatic disease.
Educational Activities
I have an appointment in the Department of Laboratory Medicine and Pathobiology at the University of Toronto and I supervise graduate students, post-doctoral fellows and summer students.
Contact
Phone: 416-864-6060 Ext. 3147
Fax: 416-864-5648
E-mail: Prudhommeg@smh.ca
