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Keenan Research Centre

Scientist Profiles

C. David Mazer

MD with great distinction, University of Saskatchewan

Affiliations

Adjunct Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital

Professor, Department of Anesthesia, University of Toronto

Professor, Department of Physiology (cross appointment), University of Toronto

Vice-Chair for Research, Department of Anesthesia, University of Toronto

Research Interests

Cardiovascular physiology, blood substitutes, anesthesiology, cardiac metabolism, critical care, cardiac surgery

Selected Publications

Link to Pub Med

Research Activities

My research interests include cardiac anesthesia and critical care. My basic science program focuses on perioperative blood conservation, cardiac physiology and metabolism and perioperative organ protection. Using integrative and molecular approaches, I investigate the adverse effects of cardiopulmonary bypass on renal function, the potential use of hemoglobin-based oxygen carriers as blood substitutes and nutrient supplementation as a protective strategy for myocardial protection. I am actively engaged in translational research as an investigator in both pre-clinical and clinical studies in these areas.

Other Activities

1. Vice-Chair, Research Advisory Committee, Canadian Anesthesiologists' Society
2. Core Member, Research Advisory Committee, Canadian Anesthesiologists' Society
3. Member, Cardiac Surgery Consensus Panel, Cardiac Care Network of Ontario
4. Member, McSPI (Multicenter Studies of Perioperative Ischemia)
5. Member, Scientific Program Committee, Society of Cardiovascular Anesthesiologists
6. Invited Reviewer, Critical Care Medicine
7. Member, Editorial Board, Canadian Journal of Anesthesia
8. Member, Board of Directors, Society of Cardiovascular Anesthesiologists
9. Past President, Cardiovascular/Thoracic Section of the Canadian Anesthesiologists' Society

Educational Activities

I am cross-appointed with the Department of Physiology in the Institute of Medical Science at the University of Toronto and am willing to accept graduate students and/or postdoctoral fellows.

Contact

Phone: 416-864-5825
Fax: 416-864-6014
E-mail: MazerD@smh.ca