Keenan Research Centre
Scientist Profiles
Andrew J. Baker
MD, University of Toronto; FRCPC, University of Toronto
Affiliations
Chief, Department of Critical Care, St. Michael's Hospital
Medical Director, Trauma and Neurosurgery Program, St. Michael's Hospital
Director, Cara Phelan Centre for Trauma Research, St. Michael's Hospital
Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital
Professor, Departments of Anesthesia and Surgery, University of Toronto
Research Interests
Traumatic brain injury, trauma and coagulation, blast-induced brain injury, neuro-biomarkers, white matter injury, AMPA receptors
Selected Publications
Research Activities
The Trauma and Neurosurgery Program and ICU are academic units with infrastructure and a culture supporting clinical research. Currently we are evaluating novel neuro-biomarkers following severe and mild traumatic brain injury and sub-arachnoid hemorrhage. We have several multi-disciplinary clinical research projects. The Cara Phelan Centre for Trauma Research supports the Traumatic Brain Injury Laboratory and has cell culture, imaging, two electrophysiological rigs, a physiological set-up, molecular biology as well as histochemistry. We have developed a controlled blast injury model and are evaluating the attendant brain injury and use several techniques including calcium imaging, EP, and in vitro stretch to look at AMPA receptor trafficking and controlling mechanisms. We also perform physiological experiments evaluating the role of different levels of anemia and different fluid resuscitation protocols on brain physiology.
Other Activities
- Board Member, Trillium Gift of Life Network
- Board Member and Chair Grants Committee, Physician Services Incorporated Foundation
Educational Activities
I have an appointment in the School of Graduate Studies and the Institute of Medical Science (IMS), University of Toronto. I am mentoring neuro-trauma-critical care fellows in clinical research and supervising one PhD and one M.Sc. IMS student candidates. I am interested in accepting new students.
Contact
Phone: 416-864-5510
Fax: 416-864-5512
E-mail: BakerA@smh.ca
