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Laboratory Medicine

Test catalogue

TSH Receptor Antibodies (TRAb, Thyroid Stimulating Immunoglobulin, TSI)

Test Name

TSH Receptor Antibodies (TRAb, Thyroid Stimulating Immunoglobulin, TSI)

Gold Tube Specimen Type/Requirements

Container Type = 1 Gold Top

Minimum Volume = 1mL Serum

Collect pediatric sample in red or yellow microtainer

Cord blood is also acceptable.

Specimen Handling

Collection Instructions: Collect sample in gold top (SST) or red top tube. Write your initials, date and time of collection on the collection label or requisition.

Laboratory Staff Instructions: Serum should be separated from cells within 1 hour. Once seperated, sample should be frozen until time of testing. Avoid repeated freezing and thawing.

Rejection criteria: Plasma, grossly lipemic, grossly hemolysed, mislabeled or samples of non sufficient quantity.

Stability: Stable refrigerated at 2-8◦C for 72 hours and frozen for 1 month at -20°C or lower.

Transportation: Send sample to core lab as soon as possible.

Required Documentation

Turnaround time (TAT)

7 days

Test Utilization

Reference Value

Therapeutic:

Normal: < 1.0 U/L;
Borderline: 1.0-2.0 U/L;
Abnormal: >2.0 U/L

 

Cord:

Normal <= 2 IU/L
Elevated > 2 IU/L
Values greater than 4 IU/L are at higher
risk of developing neonatal hyperthyroidism

Test Code

TSII

Methodology

Electrochemiluminescence Immunoassay (ECLIA)

Testing Location

SMH-Biochemistry

Other Information

Last Updated: September 30, 2020