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Laboratory Medicine

Test catalogue

Maternal Serum Screen

Test Name

Maternal Serum Screen (MSS)

Gold Tube Specimen Type / Requirements

Container Type = Gold (SST)

Minimum Volume = 1ml Serum

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions: Collect in Gold-Top Serum (SST), free from hemolysis. Separate serum from cells within 2 hours of collection

Write your initials, date and time of collection on the collection label.

Stability: Stable at room temperature for 8 hours, refrigerated for 6 days and frozen at -20°C for at least 6 months.

Transportation: Transport at room temperature ASAP. Spin if sample time of collection to time sample get to lab exceeds 2hrs.

Laboratory Staff Instructions: Separate serum or plasma from cells within 2 hours of collection.

Sample Rejection Criteria: Grossly hemolyzed samples, Unlabeled or Not Sufficient Quantity Samples will be rejected.

Required Documentation

Turnaround Time (TAT)

6 Days

Test Utilization

Once per Pregnancy

Reference Value

See Interpretative Report

Test code



Trisomy 21 and 18 Risks. Ultrasound and / or LMP, Bloodwork done between 14-20+6 GA

Testing Location

Referred Out – ON, Canada (ROMSN04)

Other Information