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Laboratory Medicine

Test catalogue

Autoimmune Encephalitis Panel, Serum

Test Name

Autoimmune Encephalitis Panel, (NMDAR, Anti-DPPX, Anti-AMPA, Anti-GABAB, Anti-GAD65, Anti-IgLON65, Anti-LGI1, Anti-CASPR2), Serum

Gold Tube Specimen Type / Requirements

Adult

Container Type = 1 Gold Top or Red top

Minimum Volume = 2mL Serum

Tubes must fill to at least ½ or greater of its vacuum capacity

Pediatric:

0-2 years: Red 0.5 Microtainer

2-10 yrs: 2 mL Red top

CSF Sample are also acceptable.

Specimen Handling

Collection Instructions: Collect sample in a red or gold top tube with or without gel separator. Please note that EDTA, heparin and citrate plasma is also acceptable Ensure sample is mixed appropriately. Biochemist approval is required prior to ordering this test Write your initials, date and time of collection on the collection label.

Please Note: Encephalitis orders require a Clinical Questionnaire to be filled out.

Laboratory Staff Instructions: Send all serum and CSF samples to ICL. Separate from cells within 2 hours of collection. Samples can be sent without clinican form. Fax questionnaire to testing site once it becomes available. Store and send frozen.

Stability: Sample can be stored for up to 14 days at 4°C. For longer storage, store at -20°C.

Rejection Criteria: Unlabeled or samples of non sufficient quantity.

Transportation: Send samples together with a completely filled out questionnaire to core lab as soon as possible.

Required Documentation

Turnaround Time (TAT)

15 days

Test Utilization

Reference Value

Negative

Test Code

AENPS

Methodology

Immunofluorescence Assay (IFA) and cell-based assay

Testing Location

Referred Out – ON, Canada (ROICL02)

Other Information

Last Updated: March 04, 2020