Our priority is to ensure the safety and well-being of our patients and residents, and our people.

Emergency department outbreak information >>

Only pre-approved visitors can visit patients at our sites. Please check our COVID-19 information page to learn more about what to expect for your appointment/visit and how to be approved as a visitor. >>

Book an appointment online for COVID-19 testing at one of our Assessment Centres. >>

Text size: a a a

Laboratory Medicine

Test catalogue

Cold Agglutinin Screen

Test Name

Cold Agglutinin Screen

Pink Tube Specimen Type / Requirements

Container Type = 2 Pink Tops

Minimum Venous Volume = 2 x 7 mL EDTA specimen (Pink Top)

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions: Collected sample in 2 Pink Top tubes and maintain at 37°C in a thermos filled with warm water. Requisition must have ordering physician, phlebotomist signature, collection date and time. Diagnosis, transfusion and pregnancy history included if applicable.

Stability: Stable at 37°C for 2 hrs.

Transportation: Use thermos with warm water (37°C) to transport specimen in biohazard bag to TM as soon as possible.

Sample Rejection Criteria: Specimen not in 37°C warm water. Grossly hemolytic, icteric or lipemic specimens. Unlabeled and/or mislabeled specimens. Incomplete TM requisitions.

Required Documentation

Ensure requisition is complete with ordering physician name and phlebotomist signature, date and time of draw.

Turnaround Time (TAT)

1 business day, if positive, may require longer TAT.

Test Utilization

As Required

Reference Value

Cold Agglutinin Screen: Negative

Test Code




Testing Location

SMH-Transfusion Medicine (Blood Bank)

Other Information

Last Updated: May 20, 2020