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Laboratory Medicine

Test catalogue

Alpha-1-Antitrypsin Clearance, Feces + Serum

Test name

Alpha-1-Antitrypsin Clearance, Feces + Serum

Fecal Container Specimen Type / Requirements

Container Type = Collection kit from Core Lab

Minimum Volume = Entire Collection

Specimen Handling

Collection Instructions: Obtain fecal collection kit from Core Lab and submit entire 24-hour collection. If no specimen is obtained in 24 hours, extend collection to 48 to 72 hours. Ensure both collection container and requisition are correctly labelled. Note: Blood sample for Alpha-1-Antitrypsin must be drawn during the fecal collection period.

Write your "start" and "end" date and time of collection on the collection label or requisition.

Laboratory Staff Instructions: Feces and serum must be submitted together. Do not use A1ATR code for serum if clearance (serum & faeces) is ordered. Use MISCS for both serum and faeces and send samples together. Store and send frozen. No approval required.

Stability: Faeces Stability: Room Temperature: 14 days. Refrigerated: 14 days. Frozen: 14 days.
                Serum Stability : Frozen 28days, refrigerated 28days, ambient 28 days.

Sample Rejection Criteria: Leaking or unlabeled specimen will be rejected.

Transportation: Send sample to SMH core lab as soon as possible.

Required Documentation

Turnaround Time (TAT)

6 Days

Test Utilization

Reference Value

Clearance: ≤27 mL/24 h

Fecal A1AT: ≤54 mg/dL

Serum A1AT: 100 - 190 mg/dL

Test Code

Use MISCS for both faeces and serum



Testing Location

Referred Out – ON, Canada (ROICL02)

Other Information

Last Updated: February 12, 2020