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Laboratory Medicine

Test catalogue

Azathioprine Metabolites

Test Name

Azathioprine Metabolites (6-Thioguanine, 6-TG, 6-Methylmercaptopurine, 6-MMP, Immunosuppressant, Immuran )

Lavender Tube Specimen Type / Requirements

Container Type = 1 Lavender (EDTA)

Minimum Volume = 5 ml Whole Blood

Tube must fill to at least ½ or greater of its vacuum capacity

Specimen Handling

Collection Instructions:

Collect sample in Lavender (Purple EDTA)top. Collect trough specimen 0-30 minutes prior to next dose. Write your initials, date and time of collection on the collection label.

Laboratory Staff Instructions

Send whole blood at room temperature

Rejection Criteria:

Serum or plasma. Unlabeled or Not Sufficient Quantity Samples will be rejected.

Transportation:

Send sample to core lab as soon as possible.

Required Documentation

Turnaround Time (TAT)

10 Days

Test Utilization

Routine >10 Days

Reference Value

6-Methylmercaptopurine (6-MMP)

Therapeutic: < 6600 pmol/8x10*8 RBC

Critical: > 6600 pmol/8x10*8 RBC

6-Thioguanine (6-TG)

400 - 750 pmol/8x10*8 RBC

Test Code

AZAMT

Methodology

HPLC

Testing Location

Referred Out – ON, Canada (ROICL02)

Other Information