Neuroscience Research Program


Theme Lead - R. Loch Macdonald

St. Michael’s neuroscientists are leaders in the field of ischemic and hemorrhagic stroke. Scientists are investigating the causes of delayed neurological deterioration after subarachnoid hemorrhage through the use of animal models, as well as studies testing learning and memory and changes in brain electrophysiology, gene expression and function. Clinical trials and knowledge translation in ischemic stroke and subarachnoid hemorrhage are also major research areas where researchers at St. Michael’s are world-wide coordinators. St. Michael’s neuroscientists are investigating the influence of the type of hospitalization, sociodemographic and health service factors on patient outcomes, among many other projects.

Areas of research St. Michael’s neurovascular scientists are investigating include:
  • Aneurismal subarachnoid hemorrhage and cerebral vasospasm.
  • Causes of delayed neurological deterioration after subarachnoid hemorrhage
  • Large artery vasospasm after aneurismal subarachnoid hemorrhage and effects of
  • Pathophysiology of intracerebral and subdural hemorrhage.
  • Brain vascular malformations and cerebral aneurysms.
  • Neurovascular clinical trials
  • Identifying neurocognitive and functional consequences of brain aneurysms.
  • Developing imaging based surrogate markers of outcome in stroke.
  • Stroke outcome and quality of care.
  • Stroke therapy (translating new emerging therapies into clinical practice).
  • Epidemiology of cerebrovascular disease.

Stroke Outcomes Research Centre

For more information about the Stroke Outcomes Research Centre click here.

What is a Subarachnoid Hemorrhage?

Research on Subarachnoid Hemorrhage

St. Michael's Neurovascular Centre

For more information about the St. Michael's Hospital Neurovascular Centre, our faculty and patient education please visit our website.

The Subarachnoid Hemorrhage International Trialists (SAHIT)

For more information about the Subarachnoid Hemorrhage International Trialists (SAHIT), click here.