Neuroscience Research Program
MD PhD MBA
Scientist in the Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital
Dorothy Pitts Chair, Ophthalmology and Vision Sciences, St. Michael's Hospital
Research InterestsGlaucoma, Degeneration of Vision Pathways, Neuroprotection and Pharmacological Treatment Strategies, Intraocular Pressure Regulation, The Role of the Lymphatic Circulation in the Eye, Neuroimaging and Clinical Trials
Phone: 416 864 5444
Khan, A. M., Kagan, D. B., Gupta, N., Navajas, E. V., Jin, Y. P., & Yucel, Y. H. (2012). Ciliary Body Lymphangiogenesis in Uveal Melanoma with and without Extraocular Extension. Ophthalmology, 120(2), 306-310.
Kanjee, R., Yucel, Y. H., Steinbach, M. J., González, E. G., & Gupta, N. (2012). Delayed saccadic eye movements in glaucoma. Eye, 4, 63-68.
Tam, A. L. C., Gupta, N., Zhang, Z., & Yucel, Y. H. (2011). Quantum dots trace lymphatic drainage from the mouse eye. Nanotechnology, 22(42), 425101.
Kim, M., Johnston, M. G., Gupta, N., Moore, S., & Yucel, Y. H. (2011). A model to measure lymphatic drainage from the eye. Experimental Eye Research, 93(5), 586-591.
Ly, T., Gupta, N., Weinreb, R. N., Kaufman, P. L., & Yucel, Y. H. (2011). Dendrite plasticity in the lateral geniculate nucleus in primate glaucoma. Vision research, 51(2), 243-250.
Yucel, Y. H., Johnston, M. G., Ly, T., Patel, M., Drake, B., Gümüş, E., ... & Gupta, N. (2009). Identification of lymphatics in the ciliary body of the human eye: a novel “uveolymphatic” outflow pathway. Experimental eye research,89(5), 810-819.
Gupta, N., Greenberg, G., de Tilly, L. N., Gray, B., Polemidiotis, M., & Yucel, Y. H. (2009). Atrophy of the lateral geniculate nucleus in human glaucoma detected by magnetic resonance imaging. British Journal of Ophthalmology,93(1), 56-60.
I have a longstanding and broad interest in glaucoma research, covering a variety of topics. These include the neuropharmacology of glaucoma, glaucoma as a neurodegenerative disease, neuroprotection strategies, the regulation of intraocular pressure, and the lymphatic circulation. Studies in the laboratory support and complement ongoing clinical studies and trials. Future work will leverage the newly founded Human Eye Biobank for Research co-founded with Yeni Yucel at the Li Ka Shing Knowledge Institute.
Appointments are held with the departments of Ophthalmology and Vision Sciences, the Institute of Medical Science and Laboratory Medicine and Pathobiology. Undergraduate students in the summer and throughout the year are welcome, as are graduate students pursuing a Master\\\\\\\'s or PhD degree and research fellows.